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Abstract
Tracheobronchomegaly or Mounier-Kuhn syndrome is a rare condition affecting the airways and is characterized by dilatation of the trachea and major bronchi secondary to atrophic or absent elastic fibres of the cartilage and thinning of the muscles.[1] The abnormally enlarged flaccid portions of the bronchial tree collapse and fail to maintain patency during expiration and coughing, predisposing the patient to stagnation of contents and recurrent lower respiratory tract infections, emphysema, bronchiectasis and chronic pulmonary suppuration.[2] The diagnosis is usually made on basis of specific radiographic features,[3] particularly on computed tomography (CT) scan. We report a case of a 69-year-old man who presented with recurrent lower respiratory tract infections and was found to have tracheobronchomegaly as an underlying primary airway abnormality on imaging and bronchoscopy that was initially undiagnosed.
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References
- Woodring JH, Howard RS, Rehm SR. Congenital tracheobronchomegaly (Mounier-Kuhn syndrome): a report of 10 cases and review of the literature. J Thorac Imaging 1991;6(2 Suppl):1-10.
- Johnston R, Green R. Tracheobronchiomegaly: report of five cases and demonstration of familial occurrence. Am Rev Respir Dis 1965;91(1):35-50.
- Krustins E. Mounier-Kuhn syndrome: a systematic analysis of 128 cases published within last 25 years. Clin Respir J 2016;10(1):3-10.
- Al Attia HM. Mounier Kuhn syndrome is another rare cause for a long standing dyspnea. Imaging Med 2018;10(6):143-6.
- Katz I, Levine M, Herman P. Tracheobronchiomegaly. The Mounier-Kuhn syndrome. Am J Roentgenol Radium Ther Nucl Med 1962;88:1084-94.
- Shin MS, Jackson RM, Ho KJ. Tracheobronchomegaly (Mounier-Kuhn syndrome): CT diagnosis. AJR Am J Roentgenol 1988;150(4):777-9.
- Menon B, Aggarwal B, Iqbal A. Mounier-Kuhn syndrome: report of 8 cases of tracheobronchomegaly with associated complications. South Med J 2008;101(1):83-7.
- Fraser R. Diagnosis of diseases of the chest. Philadelphia (Pa): WB Saunders 1991.
- Dunne MG, Reiner B. CT features of tracheobronchomegaly. J Comput Assist Tomogr 1988;12(3):388-91.
- Celik B, Bilgin S, Yuksel C. Mounier-Kuhn syndrome: a rare cause of bronchial dilation. Tex Heart Inst J 2011;38(2):194-6.
- Krustins E, Kravale Z, Buls A. Mounier-Kuhn syndrome or congenital tracheobronchomegaly: a literature review. Respir Med 2013;107(12):1822-8.
- Chandran A, Sagar P, Bhalla AS, et al Mounier-Kuhn syndrome BMJ Case Reports CP2021;14:e239876.
- Barrie HJ, Harding HE. Argyro-siderosis of the lungs in silver finishers. Br J Ind Med 1947;4(4):225-9.
- Mclaughlin A, Grout J, Barrie H, et al. Iron oxide dust and the lungs of silver finishers. Lancet 1945;245(6342):337-41.
References
Woodring JH, Howard RS, Rehm SR. Congenital tracheobronchomegaly (Mounier-Kuhn syndrome): a report of 10 cases and review of the literature. J Thorac Imaging 1991;6(2 Suppl):1-10.
Johnston R, Green R. Tracheobronchiomegaly: report of five cases and demonstration of familial occurrence. Am Rev Respir Dis 1965;91(1):35-50.
Krustins E. Mounier-Kuhn syndrome: a systematic analysis of 128 cases published within last 25 years. Clin Respir J 2016;10(1):3-10.
Al Attia HM. Mounier Kuhn syndrome is another rare cause for a long standing dyspnea. Imaging Med 2018;10(6):143-6.
Katz I, Levine M, Herman P. Tracheobronchiomegaly. The Mounier-Kuhn syndrome. Am J Roentgenol Radium Ther Nucl Med 1962;88:1084-94.
Shin MS, Jackson RM, Ho KJ. Tracheobronchomegaly (Mounier-Kuhn syndrome): CT diagnosis. AJR Am J Roentgenol 1988;150(4):777-9.
Menon B, Aggarwal B, Iqbal A. Mounier-Kuhn syndrome: report of 8 cases of tracheobronchomegaly with associated complications. South Med J 2008;101(1):83-7.
Fraser R. Diagnosis of diseases of the chest. Philadelphia (Pa): WB Saunders 1991.
Dunne MG, Reiner B. CT features of tracheobronchomegaly. J Comput Assist Tomogr 1988;12(3):388-91.
Celik B, Bilgin S, Yuksel C. Mounier-Kuhn syndrome: a rare cause of bronchial dilation. Tex Heart Inst J 2011;38(2):194-6.
Krustins E, Kravale Z, Buls A. Mounier-Kuhn syndrome or congenital tracheobronchomegaly: a literature review. Respir Med 2013;107(12):1822-8.
Chandran A, Sagar P, Bhalla AS, et al Mounier-Kuhn syndrome BMJ Case Reports CP2021;14:e239876.
Barrie HJ, Harding HE. Argyro-siderosis of the lungs in silver finishers. Br J Ind Med 1947;4(4):225-9.
Mclaughlin A, Grout J, Barrie H, et al. Iron oxide dust and the lungs of silver finishers. Lancet 1945;245(6342):337-41.