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Abstract

Iridocorneal endothelial (ICE) syndrome is a rare ophthalmic disorder, wherein the basic pathology is an abnormal corneal endothelium that leads to varying degrees of corneal oedema, iris atrophy, and secondary angle closure glaucoma.[1] This syndrome typically affects young women unilaterally with no family history.[2] The true aetiology of ICE syndrome is unclear. Viral cause for the disease has been proposed, based on a history of inflammation in certain cases and on the presence of inflammatory cells on histological analysis.[3] The abnormal endothelial cells may migrate posteriorly, forming a membrane that covers the adjacent structures, iris and trabecular meshwork.[4] The contraction of this membrane leads to characteristic iris changes, iridotrabecular synechiae, and corectopia with the pupil being drawn towards the area where the synechiae are most prevalent and to secondary angle-closure glaucoma.[5]

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Manohar Sungar, Mallikarjun Heralgi, & Roopasree Bhadrappanavar Vishwamurthy. (2022). Iridocorneal Endothelial Syndrome – A Case Report. Journal of Evolution of Medical and Dental Sciences, 11(13), 930–932. https://doi.org/10.14260/jemds.v11i13.294
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References

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